Thymosin Beta-4
Research profile · How we handle evidence
The original, full-length version of TB-500. It is found naturally in your body and plays a key role in wound healing and tissue repair. Helps cells migrate to injury sites.
Evidence Score
Preliminary signal
Category
Therapeutic area
Standard Dose
2x weekly
Half-life
Plasma elimination
Route
Oral
Safety Tier
Limited data
Overview
Thymosin Beta-4 is the natural protein your body already makes to heal itself. When you get injured, this peptide tells your cells 'go fix that damage.' It's the parent molecule that TB-500 was based on. While TB-500 is the more popular fragment, the full-length Thymosin Beta-4 has the complete healing signal your body recognizes perfectly. Great for systemic healing throughout the body.
Mechanism of Action
Thymosin Beta-4 is the natural protein your body already makes to heal itself. When you get injured, this peptide tells your cells 'go fix that damage.' It's the parent molecule that TB-500 was based on. While TB-500 is the more popular fragment, the full-length Thymosin Beta-4 has the complete healing signal your body recognizes perfectly. Great for systemic healing throughout the body.
pH & Mixing
Peptides reconstituted at very different pH levels can destabilize when combined in the same syringe, which lowers how much of the peptide your body actually absorbs. If you're unsure whether two peptides are close enough in pH, reconstitute and inject them separately.
A dedicated compatibility check between two specific peptides is coming to the Compare tool. This section covers this peptide's pH only.
Benefits
- Promotes cell migration to injuries
- Reduces inflammation
- Supports heart tissue repair
- Helps with wound healing
Side Effects
- Well-tolerated
- Possible fatigue
- Rare flu-like symptoms
Contraindications
- Pregnant or breastfeeding women
- Individuals under 18 years old
- Those with known allergies to peptide components
Structure & Sequence
Verified structure
Thymosin Beta-4
Sequence illustration backed by PubChem match.
- Amino Acid Sequence
- Ac-SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES (43aa)
- Molecular Weight
- 4,963.55 Da
- Chemical Formula
- C212H350N56O78S
- CAS Number
- 68276-72-6
- Reconstituted pH
- 4.5
- InChIKey
- UGPMCIBIHRSCBV-UHFFFAOYSA-N
Stack & Route Context
Stacks with
- BPC-157
- GHK-Cu
Administration
Oral
Research Status
Parent compound of TB-500
Approval Status
Research
Sports Legal
Restricted
References
- 1View source
A Study of the Safety and Efficacy of Injectable Thymosin Beta 4 for Treating Acute Myocardial Infarction (ClinicalTrials.gov)
2011
- 2View source
Study of Thymosin Beta 4 in Patients With Venous Stasis Ulcers (ClinicalTrials.gov)
2008
This profile summarizes research literature for education only. It is not medical advice, and it does not diagnose, treat, or recommend a dose. Consult a qualified professional before changing a protocol.