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Teriparatide

Research profile · How we handle evidence

Synthetic parathyroid hormone fragment that stimulates bone formation and increases bone mineral density.

Evidence Score

68/100

High confidence

Category

Bone Health

Therapeutic area

Standard Dose

20mcg daily

Daily

Half-life

~1 hr

Plasma elimination

Route

SC

Subcutaneous

Safety Tier

3

Limited data

Overview

Teriparatide is a fragment of parathyroid hormone that builds bone. It's one of the most effective treatments for osteoporosis, stimulating new bone formation rather than just preventing bone loss.

Mechanism of Action

Teriparatide is a fragment of parathyroid hormone that builds bone. It's one of the most effective treatments for osteoporosis, stimulating new bone formation rather than just preventing bone loss.

Bone HealthWellness

pH & Mixing

~4.0

Peptides reconstituted at very different pH levels can destabilize when combined in the same syringe, which lowers how much of the peptide your body actually absorbs. If you're unsure whether two peptides are close enough in pH, reconstitute and inject them separately.

A dedicated compatibility check between two specific peptides is coming to the Compare tool. This section covers this peptide's pH only.

Benefits

  • Bone formation stimulation
  • Increased bone density
  • Fracture prevention
  • Osteoporosis treatment

Side Effects

  • Dizziness
  • Nausea
  • Leg cramps
  • Hypercalcemia

Contraindications

  • Pregnancy
  • Bone cancer
  • Hypercalcemia
  • Radiation therapy

Structure & Sequence

View 3D structure

Verified structure

Teriparatide

Sequence illustration backed by PubChem match.

Verified via PubChemMatched by casNumber
C181H291N55O51S24,117.8 DaCAS 52232-67-434 residues
Source: PubChemLookup: 52232-67-4InChIKey OGBMKVWORPGQRR-UMXFMPSGSA-N
Amino Acid Sequence
SVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNF (PTH 1-34)
Molecular Weight
4,117.8 Da
Chemical Formula
C181H291N55O51S2
CAS Number
52232-67-4
Reconstituted pH
~4.0
InChIKey
OGBMKVWORPGQRR-UMXFMPSGSA-N

Stack & Route Context

Stacks with

  • Abaloparatide

Administration

Subcutaneous

Research Status

FDA approved for osteoporosis

Approval Status

Approved

Sports Legal

Restricted

References

No references listed.

This profile summarizes research literature for education only. It is not medical advice, and it does not diagnose, treat, or recommend a dose. Consult a qualified professional before changing a protocol.

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