TB-500 Fragment
Research profile · How we handle evidence
Shorter fragment of TB-500 with targeted healing properties and reduced side effects.
Evidence Score
Preclinical signal
Category
Therapeutic area
Standard Dose
Daily
Half-life
Plasma elimination
Route
Subcutaneous
Safety Tier
Limited data
Overview
TB-500 Fragment is the shorter, more targeted version of the full TB-500 peptide, think of it as isolating the most active healing sequence without the rest of the molecule. It retains the actin-binding and cell migration properties that make TB-500 so effective for tissue repair, but with a faster onset and potentially fewer side effects. It's popular for localized injury recovery where you want concentrated healing without systemic effects. That said, most experienced users prefer full-length TB-500 (Thymosin Beta-4) because the complete molecule has decades more research behind it and the fragment loses some of the anti-inflammatory breadth. If you're trying it, stack with BPC-157 and apply it close to the injury site for best results.
Mechanism of Action
TB-500 Fragment is the shorter, more targeted version of the full TB-500 peptide, think of it as isolating the most active healing sequence without the rest of the molecule. It retains the actin-binding and cell migration properties that make TB-500 so effective for tissue repair, but with a faster onset and potentially fewer side effects. It's popular for localized injury recovery where you want concentrated healing without systemic effects. That said, most experienced users prefer full-length TB-500 (Thymosin Beta-4) because the complete molecule has decades more research behind it and the fragment loses some of the anti-inflammatory breadth. If you're trying it, stack with BPC-157 and apply it close to the injury site for best results.
pH & Mixing
Peptides reconstituted at very different pH levels can destabilize when combined in the same syringe, which lowers how much of the peptide your body actually absorbs. If you're unsure whether two peptides are close enough in pH, reconstitute and inject them separately.
A dedicated compatibility check between two specific peptides is coming to the Compare tool. This section covers this peptide's pH only.
Benefits
- Targeted tissue repair
- Reduced side effects
- Faster action
- Systemic healing
Side Effects
- Generally well-tolerated
- Mild fatigue
Contraindications
- Pregnant or breastfeeding women
Structure & Sequence
Verified structure
TB-500 Fragment
Illustration uses the catalog amino acid sequence because no exact external registry match was confirmed.
- Amino Acid Sequence
- Ac-LKKTETQ (TB-500 fragment, residues 17-23 of Thymosin Beta-4)
- Molecular Weight
- 877.99 Da
- Chemical Formula
- C39H67N9O13
- CAS Number
- 885340-08-9
- Reconstituted pH
- 7.4
Stack & Route Context
Stacks with
- BPC-157
- GHK-Cu
Administration
Subcutaneous
Research Status
Research peptide for healing
Approval Status
Preclinical
Sports Legal
Permitted
References
- 1View source
Study of Thymosin Beta 4 in Patients With Venous Stasis Ulcers (ClinicalTrials.gov)
2008
This profile summarizes research literature for education only. It is not medical advice, and it does not diagnose, treat, or recommend a dose. Consult a qualified professional before changing a protocol.