SNAP-8
Research profile · How we handle evidence
Octapeptide that may reduce the look of wrinkles driven by facial muscle tension, especially around the eyes and forehead.
Evidence Score
High confidence
Category
Therapeutic area
Standard Dose
Daily topical application
Half-life
Plasma elimination
Route
Topical
Safety Tier
Well characterized
Overview
SNAP-8 is a topical peptide that can help reduce the look of muscle-driven expression lines around the eyes and forehead.
Mechanism of Action
SNAP-8 is a topical peptide that can help reduce the look of muscle-driven expression lines around the eyes and forehead.
pH & Mixing
Peptides reconstituted at very different pH levels can destabilize when combined in the same syringe, which lowers how much of the peptide your body actually absorbs. If you're unsure whether two peptides are close enough in pH, reconstitute and inject them separately.
A dedicated compatibility check between two specific peptides is coming to the Compare tool. This section covers this peptide's pH only.
Benefits
- Reduces wrinkle depth
- Minimizes expression lines
- Non-invasive
- Topical application
Side Effects
- Mild skin irritation
- Redness
Contraindications
- Pregnant or breastfeeding women
- Sensitive skin
Structure & Sequence
Verified structure
SNAP-8
Sequence illustration backed by PubChem match.
- Amino Acid Sequence
- Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2 (Acetyl Octapeptide-3)
- Molecular Weight
- 1,075.16 Da
- Chemical Formula
- C41H70N16O16S
- CAS Number
- 868844-74-0
- Reconstituted pH
- 4.3
- InChIKey
- KMACPCJUCHVVGP-FNRPHRCSSA-N
Stack & Route Context
Stacks with
- GHK-Cu
- Matrixyl
Administration
Topical
Research Status
Cosmetic peptide for anti-aging
Approval Status
Commercial
Sports Legal
Permitted
References
- 1View source
Snap-8 (Acetyl Octapeptide-3) peptide overview and reported clinical context
2024
- 2View source
SNAP-8 dosage protocol with cited open-label clinical study context
2024
This profile summarizes research literature for education only. It is not medical advice, and it does not diagnose, treat, or recommend a dose. Consult a qualified professional before changing a protocol.