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Pinealon

Research profile · How we handle evidence

Synthetic peptide that regulates gene expression and supports cognitive function, memory, and neuroprotection.

Evidence Score

37/100

Preclinical signal

Category

Cognitive Enhancement

Therapeutic area

Standard Dose

5-20mg

Daily

Half-life

~4 hr

Plasma elimination

Route

PO / SC / IN

Oral, Subcutaneous or Intranasal

Safety Tier

3

Limited data

Overview

Pinealon is a short peptide (often described as Glu-Asp-Arg / EDR in bioregulator catalogs) in the Khavinson-family niche. It’s commonly framed around gene-expression signaling ideas and nervous-system support rather than a stimulant-style mechanism. Public discussions sometimes mention research areas like stroke recovery and cognitive aging, but most accessible material is preclinical or indirect, so keep expectations conservative. Some users stack Pinealon with Epitalon for broader “brain + longevity” support framing.

Mechanism of Action

Pinealon is a short peptide (often described as Glu-Asp-Arg / EDR in bioregulator catalogs) in the Khavinson-family niche. It’s commonly framed around gene-expression signaling ideas and nervous-system support rather than a stimulant-style mechanism. Public discussions sometimes mention research areas like stroke recovery and cognitive aging, but most accessible material is preclinical or indirect, so keep expectations conservative. Some users stack Pinealon with Epitalon for broader “brain + longevity” support framing.

CognitiveAnti Aging

pH & Mixing

4.2

Peptides reconstituted at very different pH levels can destabilize when combined in the same syringe, which lowers how much of the peptide your body actually absorbs. If you're unsure whether two peptides are close enough in pH, reconstitute and inject them separately.

A dedicated compatibility check between two specific peptides is coming to the Compare tool. This section covers this peptide's pH only.

Benefits

  • Cognitive enhancement
  • Memory improvement
  • Neuroprotection
  • Gene expression regulation

Side Effects

  • Reported as generally well-tolerated in limited user reports
  • Some users report mild headache
  • Human side-effect data is not well-established

Contraindications

  • Pregnant or breastfeeding women

Structure & Sequence

View 3D structure

Verified structure

Pinealon

Sequence illustration backed by PubChem match.

Verified via PubChemMatched by casNumber
C15H26N6O8418.4 DaCAS 175175-23-23 residues
Source: PubChemLookup: 175175-23-2InChIKey QPRZKNOOOBWXSU-CIUDSAMLSA-N
Amino Acid Sequence
Glu-Asp-Arg (EDR)
Molecular Weight
418.4 Da
Chemical Formula
C15H26N6O8
CAS Number
175175-23-2
Reconstituted pH
4.2
InChIKey
QPRZKNOOOBWXSU-CIUDSAMLSA-N

Stack & Route Context

Stacks with

  • Epitalon
  • Selank

Administration

Oral, Subcutaneous or Intranasal

Research Status

Research peptide for cognitive enhancement

Approval Status

Preclinical

Sports Legal

Permitted

References

  1. 1

    Pinealon (CAS 175175-23-2) product/structure reference page (sequence & properties)

    View source

This profile summarizes research literature for education only. It is not medical advice, and it does not diagnose, treat, or recommend a dose. Consult a qualified professional before changing a protocol.

Research-driven insights.Evidence-based decisions.