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Oxytocin

Research profile · How we handle evidence

A peptide hormone involved in social bonding, stress regulation, and reproductive physiology. It is often described in the media as the "love hormone".

Evidence Score

68/100

High confidence

Category

Hormone Balance

Therapeutic area

Standard Dose

10-50mcg

As needed

Half-life

~3 hr

Plasma elimination

Route

SC / IN

Subcutaneous or Intranasal

Safety Tier

3

Limited data

Overview

Oxytocin is a peptide hormone linked to social behavior, bonding, and aspects of stress regulation. In humans, intranasal dosing is studied mainly for how it may affect social attention, trust-related signals, and emotional processing in specific contexts. The effects in research are mixed and can be subtle, so it is not a switch that creates instant warmth toward everyone. Timing and context seem to matter, and some studies suggest the hormone can change how social cues are interpreted (including potentially shifting both positive and negative social memory recall).

Mechanism of Action

Oxytocin is a peptide hormone linked to social behavior, bonding, and aspects of stress regulation. In humans, intranasal dosing is studied mainly for how it may affect social attention, trust-related signals, and emotional processing in specific contexts. The effects in research are mixed and can be subtle, so it is not a switch that creates instant warmth toward everyone. Timing and context seem to matter, and some studies suggest the hormone can change how social cues are interpreted (including potentially shifting both positive and negative social memory recall).

Sexual HealthWellnessHormone Balance

pH & Mixing

3.0-5.0

Peptides reconstituted at very different pH levels can destabilize when combined in the same syringe, which lowers how much of the peptide your body actually absorbs. If you're unsure whether two peptides are close enough in pH, reconstitute and inject them separately.

A dedicated compatibility check between two specific peptides is coming to the Compare tool. This section covers this peptide's pH only.

Benefits

  • Social bonding
  • Trust enhancement
  • Anxiety reduction
  • Relationship support
  • Maternal behaviors

Side Effects

  • Mild headache
  • Nausea
  • Dizziness
  • Emotional sensitivity

Contraindications

  • Pregnant or breastfeeding women
  • History of uterine contractions

Structure & Sequence

View 3D structure

Verified structure

Oxytocin

Sequence illustration backed by PubChem match.

Verified via PubChemMatched by name
C43H66N12O12S21,007 Da9 residues
Source: PubChemLookup: OxytocinInChIKey XNOPRXBHLZRZKH-DSZYJQQASA-N
Amino Acid Sequence
CYIQNCPLG-NH2 (disulfide bridge Cys1-Cys6)
Cyclization
Disulfide-bridged
Molecular Weight
1,007 Da
Chemical Formula
C43H66N12O12S2
CAS Number
N/A
Reconstituted pH
3.0-5.0
InChIKey
XNOPRXBHLZRZKH-DSZYJQQASA-N

Stack & Route Context

Stacks with

  • Kisspeptin
  • PT-141

Administration

Subcutaneous or Intranasal

Research Status

Well-studied hormone with established uses

Approval Status

Approved

Sports Legal

Permitted

References

No references listed.

This profile summarizes research literature for education only. It is not medical advice, and it does not diagnose, treat, or recommend a dose. Consult a qualified professional before changing a protocol.

Research-driven insights.Evidence-based decisions.