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GHRP-2

Research profile · How we handle evidence

One of the strongest growth hormone releasers available. It really boosts your appetite, making it perfect if you are trying to gain weight or build muscle mass.

Evidence Score

33/100

Preliminary signal

Category

Growth Hormone

Therapeutic area

Standard Dose

100-300mcg

2-3x daily

Half-life

~2 hr

Plasma elimination

Route

SC

Subcutaneous

Safety Tier

3

Limited data

Overview

GHRP-2 is the heavy hitter of GH peptides. It tells your body to pump out a ton of growth hormone. The trade-off? You'll be HUNGRY. Great for skinny guys trying to bulk up or anyone needing serious muscle recovery.

Mechanism of Action

GHRP-2 is stronger than ipamorelin for GH release but comes with a significant hunger spike, some people can't tolerate it. GHRP-6 causes even more hunger and is better for bulking. Compared to hexarelin, which is more potent but desensitizes faster, GHRP-2 hits a sweet spot of power and sustainability.

Potent Ghrelin Receptor (GHS R1a) Agonist With Strong GH Release StimulationBinds GHS R1a In Hypothalamus And Pituitary To Trigger Pulsatile GH SecretionIncreases Appetite Through Ghrelin Mimetic Signaling In Arcuate NucleusSynergizes With GHRH Analogues For Amplified GH Pulse Amplitude

Benefits

  • Strongest GH release of its class
  • Significant muscle building
  • Better fat burning
  • Improved sleep
  • Great for bulking

Side Effects

  • Strong hunger increase
  • Water retention
  • May raise cortisol slightly
  • Possible prolactin increase

Contraindications

  • Pregnant or breastfeeding women
  • Individuals under 18 years old
  • Those with known allergies to peptide components
  • Active cancer
  • Uncontrolled diabetes

Structure & Sequence

View 3D structure

Verified structure

GHRP-2

Sequence illustration backed by PubChem match.

Verified via PubChemMatched by casNumber
C45H55N9O6817.97 DaCAS 158861-67-76 residues
Source: PubChemLookup: 158861-67-7InChIKey VJBAWMTTYDQWBO-MQENXCALSA-N
Amino Acid Sequence
D-Ala-D-2Nal-Ala-Trp-D-Phe-Lys-NH2
Molecular Weight
817.97 Da
Chemical Formula
C45H55N9O6
CAS Number
158861-67-7
InChIKey
VJBAWMTTYDQWBO-MQENXCALSA-N

Stack & Route Context

Stacks with

  • CJC-1295
  • Ipamorelin

Administration

Subcutaneous

Research Status

Research chemical

Approval Status

Research

Sports Legal

Restricted

References

  1. 1

    GHRP-2 stimulates GH secretion through pituitary receptor activation

    1994

    View source
  2. 2

    Growth hormone releasing peptides in children and adults

    2002

This profile summarizes research literature for education only. It is not medical advice, and it does not diagnose, treat, or recommend a dose. Consult a qualified professional before changing a protocol.

Research-driven insights.Evidence-based decisions.