Back to libraryCognitive Enhancement

FGL

Research profile · How we handle evidence

FGL is discussed as a peptide associated with fibroblast-growth-factor–linked pathways, usually framed around synaptic plasticity and learning/memory ideas. Published human safety and effectiveness evidence is limited, so treat the explanations as early research summaries.

Evidence Score

34/100

Preclinical signal

Category

Cognitive Enhancement

Therapeutic area

Standard Dose

5-20mg

Daily

Half-life

~4 hr

Plasma elimination

Route

SC / IN

Subcutaneous or Intranasal

Safety Tier

3

Limited data

Overview

You’ll see FGL described as a synaptic-plasticity–leaning research peptide in some protocols. The safety and risk picture for humans isn’t well established, and ‘cognitive enhancement’ language is mostly theoretical. Use it as informational context, not as a substitute for clinical advice.

Mechanism of Action

You’ll see FGL described as a synaptic-plasticity–leaning research peptide in some protocols. The safety and risk picture for humans isn’t well established, and ‘cognitive enhancement’ language is mostly theoretical. Use it as informational context, not as a substitute for clinical advice.

CognitiveWellness

pH & Mixing

6.5

Peptides reconstituted at very different pH levels can destabilize when combined in the same syringe, which lowers how much of the peptide your body actually absorbs. If you're unsure whether two peptides are close enough in pH, reconstitute and inject them separately.

A dedicated compatibility check between two specific peptides is coming to the Compare tool. This section covers this peptide's pH only.

Benefits

  • Enhanced learning
  • Memory improvement
  • Synaptic plasticity
  • Neuroprotection

Side Effects

  • Limited published human safety data—tolerability can vary. Stop if you get unexpected side effects and get medical guidance

Contraindications

  • Pregnant or breastfeeding women

Structure & Sequence

Verified structure

FGL

Illustration uses the catalog amino acid sequence because no exact external registry match was confirmed.

Sequence-backed
C71H116N20O251,649.83 Da15 residues
Amino Acid Sequence
EVYVVAENQQGKSKA
Molecular Weight
1,649.83 Da
Chemical Formula
C71H116N20O25
CAS Number
N/A
Reconstituted pH
6.5

Stack & Route Context

Stacks with

  • Semax
  • Selank

Administration

Subcutaneous or Intranasal

Research Status

Research peptide for cognitive enhancement

Approval Status

Preclinical

Sports Legal

Permitted

References

No references listed.

This profile summarizes research literature for education only. It is not medical advice, and it does not diagnose, treat, or recommend a dose. Consult a qualified professional before changing a protocol.

Research-driven insights.Evidence-based decisions.