DNSP-11
Research profile · How we handle evidence
Peptide nootropic that enhances cognitive function, memory formation, and provides neuroprotection.
Evidence Score
Preclinical signal
Category
Therapeutic area
Standard Dose
Daily
Half-life
Plasma elimination
Route
Subcutaneous or Intranasal
Safety Tier
Limited data
Overview
DNSP-11 is a synthetic peptide derived from the glial cell line-derived neurotrophic factor (GDNF) propeptide region. In preclinical research, DNSP-11 has been reported to support dopamine neuron function and show neurotrophic-like effects. Because most evidence is from animal and cell models, it's still considered an investigational research peptide rather than an established therapy. Practical note: people often discuss intranasal use for convenience, but the route and dose are not standardized across studies.
Mechanism of Action
DNSP-11 is a synthetic peptide derived from the glial cell line-derived neurotrophic factor (GDNF) propeptide region. In preclinical research, DNSP-11 has been reported to support dopamine neuron function and show neurotrophic-like effects. Because most evidence is from animal and cell models, it's still considered an investigational research peptide rather than an established therapy. Practical note: people often discuss intranasal use for convenience, but the route and dose are not standardized across studies.
pH & Mixing
Peptides reconstituted at very different pH levels can destabilize when combined in the same syringe, which lowers how much of the peptide your body actually absorbs. If you're unsure whether two peptides are close enough in pH, reconstitute and inject them separately.
A dedicated compatibility check between two specific peptides is coming to the Compare tool. This section covers this peptide's pH only.
Benefits
- Cognitive enhancement
- Memory improvement
- Neuroprotection
- Focus enhancement
Side Effects
- Generally well-tolerated
- Mild headache
Contraindications
- Pregnant or breastfeeding women
Structure & Sequence
Verified structure
DNSP-11
Illustration uses the catalog amino acid sequence because no exact external registry match was confirmed.
- Amino Acid Sequence
- PPEAPAEDRSL-NH2
- Molecular Weight
- 1,180.27 Da
- Chemical Formula
- C50H81N15O18
- CAS Number
- N/A
- Reconstituted pH
- 5.0
Stack & Route Context
Stacks with
- Semax
- Selank
- P21
Administration
Subcutaneous or Intranasal
Research Status
Research peptide for cognitive enhancement
Approval Status
Preclinical
Sports Legal
Permitted
References
- 1View source
Dopamine neuron stimulating actions of a GDNF propeptide (DNSP-11)
2010
- 2View source
Dopamine neuron stimulating actions of a GDNF propeptide
2010
- 3View source
Dynamic changes in dopamine neuron function after DNSP-11 treatment
2014
This profile summarizes research literature for education only. It is not medical advice, and it does not diagnose, treat, or recommend a dose. Consult a qualified professional before changing a protocol.