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AHK-Cu

Research profile · How we handle evidence

AHK-Cu is often discussed alongside the copper-binding tripeptide GHK-Cu. It’s generally framed in skin and wound-repair circles as a copper-associated peptide effect that may support processes like collagen remodeling, migration, and tissue repair. Human evidence is limited and varies by product and application method, so treat this as educational background rather than a guaranteed outcome.

Evidence Score

43/100

Preclinical signal

Category

Hair Skin

Therapeutic area

Standard Dose

0.1-1% topical or 1-2mg injectable

Daily topical or 2-3x weekly injectable

Half-life

~4 hr

Plasma elimination

Route

TOP / SC

Topical or Subcutaneous

Safety Tier

3

Limited data

Overview

GHK-Cu (a copper complex) is the best-known reference point here. The idea behind copper peptides in skin care is that copper–peptide complexes can influence cellular signaling involved in repair and remodeling. Clinical data depend heavily on formulation and dosing.

Mechanism of Action

GHK-Cu (a copper complex) is the best-known reference point here. The idea behind copper peptides in skin care is that copper–peptide complexes can influence cellular signaling involved in repair and remodeling. Clinical data depend heavily on formulation and dosing.

Hair SkinAnti Aging

Benefits

  • Stimulates hair growth
  • Improves skin elasticity
  • Reduces wrinkles
  • Enhances wound healing

Side Effects

  • Mild skin irritation
  • Rare allergic reactions

Contraindications

  • Pregnant or breastfeeding women
  • Those with copper allergies

Structure & Sequence

Verified structure

AHK-Cu

Illustration uses the catalog amino acid sequence because no exact external registry match was confirmed.

Sequence-backed
C15H24ClCuN6O4-451.39 DaCAS 682809-81-03 residues
Amino Acid Sequence
AHK
Molecular Weight
451.39 Da
Chemical Formula
C15H24ClCuN6O4-
CAS Number
682809-81-0

Stack & Route Context

Stacks with

  • GHK-Cu
  • TB-500

Administration

Topical or Subcutaneous

Research Status

Research peptide for hair loss

Approval Status

Preclinical

Sports Legal

Permitted

References

  1. 1

    Regenerative and protective actions of the GHK-Cu peptide in light of new gene data

    2018

    View source
  2. 2

    Skin wound healing study using GHK-Cu gel

    2024

    View source
  3. 3

    Skin regenerative and anti-cancer actions of copper peptides (review)

    2018

    View source

This profile summarizes research literature for education only. It is not medical advice, and it does not diagnose, treat, or recommend a dose. Consult a qualified professional before changing a protocol.

Research-driven insights.Evidence-based decisions.