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Adipotide

Research profile · How we handle evidence

Adipotide is an experimental peptide that’s been studied in animals for possible fat-targeting effects. The hypothesis is that it may bind to the micro-blood vessels that help sustain white fat, which could change how readily that tissue persists.

Evidence Score

37/100

Preclinical signal

Category

Fat Loss

Therapeutic area

Standard Dose

0.5-1mg/kg

Daily

Half-life

~4 hr

Plasma elimination

Route

SC

Subcutaneous

Safety Tier

3

Limited data

Overview

Adipotide isn’t supposed to behave like a straightforward “fat burner.” It’s designed around a targeting idea: aim for the small blood vessels feeding white fat. In animal work, that disruption is one proposed route to lower fat tissue survival.

Mechanism of Action

Adipotide isn’t supposed to behave like a straightforward “fat burner.” It’s designed around a targeting idea: aim for the small blood vessels feeding white fat. In animal work, that disruption is one proposed route to lower fat tissue survival.

Fat LossBody Composition

Benefits

  • Targeted fat loss
  • Reduced adipose tissue
  • Improved body composition
  • Selective fat cell apoptosis

Side Effects

  • Kidney safety concerns have been reported in higher-dose animal work
  • Injection site reactions such as redness or irritation are possible
  • Human safety and tolerability are not established

Contraindications

  • Pregnant or breastfeeding women
  • Known kidney disease
  • Those with a history of severe adverse reactions to peptides

Structure & Sequence

View 3D structure

Verified structure

Adipotide

Sequence illustration backed by PubChem match.

Verified via PubChemMatched by casNumber
C111H206N36O28S22,557.2 DaCAS 859216-15-211 residues
Source: PubChemLookup: 859216-15-2InChIKey GZESIPHLGJDZRG-VCWDIOOSSA-N
Amino Acid Sequence
CKGGRAKDC-GG-D(KLAKLAK)2
Molecular Weight
2,557.2 Da
Chemical Formula
C111H206N36O28S2
CAS Number
859216-15-2
InChIKey
GZESIPHLGJDZRG-VCWDIOOSSA-N

Stack & Route Context

Stacks with

  • HGH Frag 176-191
  • AOD-9604

Administration

Subcutaneous

Research Status

Research peptide for targeted fat loss

Approval Status

Preclinical

Sports Legal

Permitted

References

  1. 1

    Peptide reported to induce apoptosis in adipose tissue endothelium and reduce food intake/body weight (animal study)

    2009

    View source

This profile summarizes research literature for education only. It is not medical advice, and it does not diagnose, treat, or recommend a dose. Consult a qualified professional before changing a protocol.

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