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5-Amino-1MQ

Research profile · How we handle evidence

Nicotinamide N-methyltransferase (NNMT) inhibitor that promotes fat loss and improves metabolic health. Basically blocks the enzyme that tells your body to store fat, letting you burn it more efficiently instead.

Evidence Score

40/100

Preclinical signal

Category

Fat Loss

Therapeutic area

Standard Dose

50-100mg

Daily

Half-life

~8 hr

Plasma elimination

Route

PO / SC

Oral or Subcutaneous

Safety Tier

3

Limited data

Overview

5-Amino-1MQ blocks an enzyme called NNMT that tells your body to store fat. By shutting that signal off, your cells switch to burning fat instead. Most users notice changes within 4-8 weeks when combined with a decent diet. Start at 50mg daily and assess tolerance before increasing. It plays well with other metabolic peptides like AOD-9604 for amplified fat loss.

Mechanism of Action

5-Amino-1MQ blocks an enzyme called NNMT that tells your body to store fat. By shutting that signal off, your cells switch to burning fat instead. Most users notice changes within 4-8 weeks when combined with a decent diet. Start at 50mg daily and assess tolerance before increasing. It plays well with other metabolic peptides like AOD-9604 for amplified fat loss.

Fat LossMetabolic

Benefits

  • Fat loss without stimulants
  • Improved metabolic function
  • Reduces fat storage signals
  • Enhanced energy expenditure

Side Effects

  • Generally well-tolerated
  • Mild GI upset in some users

Contraindications

No entries listed.

Structure & Sequence

View 3D structure

Verified structure

5-Amino-1MQ

Exact 2D structure can be rendered from a PubChem-backed canonical SMILES string.

Verified via PubChemMatched by casNumber
Source: PubChemLookup: 685079-15-6InChIKey ZMJBCEIHNOWCMC-UHFFFAOYSA-O
Molecular Weight
159.21 Da
Chemical Formula
C10H11N2+
CAS Number
685079-15-6
InChIKey
ZMJBCEIHNOWCMC-UHFFFAOYSA-O

Stack & Route Context

Stacks with

  • AOD-9604
  • HGH Frag 176-191

Administration

Oral or Subcutaneous

Research Status

Research compound for metabolic health and fat loss. Shows promise in preclinical studies.

Approval Status

Preclinical

Sports Legal

Permitted

References

  1. 1

    5-Amino-1MQ research guide (NNMT inhibition overview)

    2024

    View source
  2. 2

    5-Amino-1MQ — product/mechanism summary

    2026

    View source

This profile summarizes research literature for education only. It is not medical advice, and it does not diagnose, treat, or recommend a dose. Consult a qualified professional before changing a protocol.

Research-driven insights.Evidence-based decisions.