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SARMPreclinical

YK-11

y-k-one-11

Research profile · How we handle evidence

Category

SARM

Compound type

Phase / Status

Preclinical

Limited research. Not FDA approved for use as a product.

Standard Dose

5-15mg

Once daily

Half-life

12-24 hours

Plasma elimination

Route(s)

OR

Oral

Research Stage

Preclinical

Animal/in-vitro data only; no human trial evidence.

Overview

YK-11 is often described as a "high potency" compound that may both interact with androgen receptors and inhibit myostatin, a protein involved in limiting muscle growth. It's treated as experimental because the strongest evidence is still preclinical, and side effects - including liver and hormone-related risks - have been reported by users.

Plain-language summary

YK-11 is often described as a "high potency" compound that may both interact with androgen receptors and inhibit myostatin, a protein involved in limiting muscle growth. It's treated as experimental because the strongest evidence is still preclinical, and side effects - including liver and hormone-related risks - have been reported by users.

Administration Routes

  • Oral

Also known as

YK11YKYK 11Myostatin BlockerMyostatin Inhibitor SARMYK-11 SARMSuper SARM

Mechanisms

1

Steroid derivative with SARM-like properties - binds to androgen receptors and inhibits myostatin. Double mechanism: turns on muscle building AND removes the natural limit on how big muscles can get.

Detailed mechanism

Steroid derivative with SARM-like properties - binds to androgen receptors and inhibits myostatin. Selectively binds to androgen receptors in muscle and bone tissue while minimizing effects on other organs, promoting anabolic effects with reduced side effects compared to traditional steroids.

Safety

Side effects

  • Testosterone suppression
  • Liver stress (risk may increase with oral anabolic compounds)
  • Hair loss (if prone)
  • Joint pain
  • Sleep disruption
  • Mood or behavioral changes

Reported benefits

  • Blocks myostatin (muscle growth limiter)
  • Binds to androgen receptors
  • Significant muscle mass gains
  • Increased strength

Safety profile

Limited human safety data. If you choose to research this topic, treat it as experimental and avoid self-medication - seek medical guidance when relevant.

Clinical trials

Preclinical studies reported. Human studies are limited.

Structure

Verified structure

YK-11

No exact public structure match was confirmed, so the app will render a formula-backed illustration.

Formula-backed
C23H28F2N2O2356.46 g/molCAS 500783-23-35 element fingerprint
Chemical Formula
C23H28F2N2O2
Molecular Weight
356.46 g/mol
CAS Number
500783-23-3

Stack Context

Stacks with

CardarineOstarineTestosterone

References

  1. 1

    Selective androgen receptor modulator YK11 regulates myogenic differentiation through follistatin (Biol Pharm Bull)

    2013

    View source
  2. 2

    Pharmacology of anabolic steroids (Br J Pharmacol review)

    2008

    View source
  3. 3

    Selective androgen receptor modulators as function promoting therapies

    2009

    View source

This profile summarizes research literature for education only. It is not medical advice, and it does not diagnose, treat, or recommend a dose. Consult a qualified professional before changing a protocol.

Research-driven insights.Evidence-based decisions.