Back to library
HormoneResearch

Trenbolone

TREN-boh-lone

Research profile · How we handle evidence

Category

Hormone

Compound type

Phase / Status

Research

Veterinary steroid; not approved for human performance use. Safety for non-medical contexts is not established.

Standard Dose

100-400mg/week (acetate: 100mg EOD, enanthate: 200-400mg/week)

Every other day (acetate) or twice weekly (enanthate)

Half-life

Trenbolone Acetate: ~3 days | Trenbolone Enanthate: ~5-7 days

Plasma elimination

Route(s)

IN

Intramuscular

Research Stage

Status Unknown

Research phase not specified; exercise appropriate caution.

Overview

Trenbolone is a potent steroid that can affect muscle and fat-related physiology, but it also has substantial risk for adverse effects. It should not be treated like a simple supplement; only medically supervised use is appropriate.

Plain-language summary

Trenbolone is a potent steroid that can affect muscle and fat-related physiology, but it also has substantial risk for adverse effects. It should not be treated like a simple supplement; only medically supervised use is appropriate.

Administration Routes

  • Intramuscular

Also known as

TrenTren ATren ETrenbolognaFinaplixParabolanFinaDevil's LettuceSatan's TestosteroneTri-Tren

Mechanisms

1

Potent androgen receptor agonist. It does not aromatize to estrogen. It can influence multiple hormone and metabolic pathways, including effects on nitrogen balance and related signaling.

Detailed mechanism

Androgen receptor agonist with non-aromatizing properties. It can modulate hormone and metabolic pathways affecting metabolism and tissue maintenance.

Safety

Side effects

  • Potential testosterone suppression and endocrine disruption
  • Possible mood and sleep changes
  • Potential cardiovascular strain depending on lipids/blood pressure
  • Possible elevated prolactin and related symptoms
  • Hair loss or acne in susceptible individuals
  • Kidney stress risk cannot be ruled out without monitoring

Reported benefits

  • Potential changes in muscle and body composition in research/informal contexts
  • Does not convert to estrogen (no aromatization)

Safety profile

Limited human safety data for non-medical use. Risks can include endocrine, cardiovascular, psychiatric, and other effects; monitoring is essential when considering any clinical scenario.

Clinical trials

Limited evidence for broad human therapeutic approval; primarily studied in veterinary and research contexts.

Structure

View 3D structure

Verified structure

Trenbolone

Exact 2D structure can be rendered from a PubChem-backed canonical SMILES string.

Verified via PubChemMatched by casNumber
Source: PubChemLookup: 10161-33-8InChIKey MEHHPFQKXOUFFV-OWSLCNJRSA-N
Chemical Formula
C18H22O2
Molecular Weight
270.37 g/mol
CAS Number
10161-33-8
InChIKey
MEHHPFQKXOUFFV-OWSLCNJRSA-N

Stack Context

Stacks with

TestosteroneCabergolineAnastrozoleBPC-157

References

  1. 1

    Pharmacology of anabolic steroids (Br J Pharmacol review)

    2008

    View source
  2. 2

    Trenbolone-enanthate normalizes androgen levels and prevents loss of bone mineral density during immobilization

    2009

    View source
  3. 3

    Effects of androgenic-anabolic steroids in athletes (Sports Medicine review)

    2004

    View source

This profile summarizes research literature for education only. It is not medical advice, and it does not diagnose, treat, or recommend a dose. Consult a qualified professional before changing a protocol.

Research-driven insights.Evidence-based decisions.