Testolone (RAD-140)
tes-oh-lone
Category
Compound type
Phase / Status
Investigational compound. Development and human study data are limited compared with approved medications. Not FDA approved for general use.
Standard Dose
Once daily
Half-life
Plasma elimination
Route(s)
Intramuscular, Subcutaneous or Oral
Research Stage
Research phase not specified; exercise appropriate caution.
Overview
Testolone (RAD-140) is a SARM being studied for selective effects on androgen receptors in tissue. Research aims to separate potential anabolic signaling from some classic steroid-like effects, but the full safety picture is still being built, including questions around hormone suppression and possible organ effects. If you are looking at this in a non-approved context, treat it as investigational and focus on risk awareness rather than "guaranteed" outcomes.
Plain-language summary
Testolone (RAD-140) is a SARM being studied for selective effects on androgen receptors in tissue. Research aims to separate potential anabolic signaling from some classic steroid-like effects, but the full safety picture is still being built, including questions around hormone suppression and possible organ effects. If you are looking at this in a non-approved context, treat it as investigational and focus on risk awareness rather than "guaranteed" outcomes.
Administration Routes
- Intramuscular
- Subcutaneous
- Oral
Also known as
Mechanisms
Selective Androgen Receptor Modulator (SARM): binds to androgen receptors in certain tissues. In research contexts, it is designed to produce anabolic signaling while differing from traditional anabolic-androgenic steroids.
Detailed mechanism
Selective Androgen Receptor Modulator (SARM): binds to androgen receptors in muscle and bone tissue. Research aims to separate anabolic effects from some steroid-like effects, but tissue selectivity and long-term safety are still being evaluated.
Safety
Side effects
- Possible suppression of natural testosterone
- Potential liver stress at elevated exposures (risk depends on dose and individual factors)
- Hair loss in those genetically predisposed
- Other individual tolerance and cardiovascular/lipid changes may occur
Reported benefits
- Potential increases in lean mass and strength in research contexts
- Oral administration
Safety profile
Limited human safety data. Risks such as hormone suppression and organ effects are possible; medical supervision is required for any clinical use of investigational agents.
Clinical trials
Limited publicly available information; not yet broadly established in formal, large-scale clinical programs.
Structure
Verified structure
Testolone (RAD-140)
No exact public structure match was confirmed, so the app will render a formula-backed illustration.
- Chemical Formula
- C19H17F2N3O
- Molecular Weight
- 360.42 g/mol
- CAS Number
- 1182366-52-7
Stack Context
Stacks with
References
- 1View source
NCT03088527 - Phase 1 first-in-human study of RAD-140 (ClinicalTrials.gov)
2017
- 2View source
Design, synthesis, and preclinical characterization of RAD-140 (ACS Medicinal Chemistry Letters)
2011
- 3View source
RAD-140 and drug-induced liver injury signals reported in human case studies (Clinical and Experimental Pharmacology & Physiology)
2023
This profile summarizes research literature for education only. It is not medical advice, and it does not diagnose, treat, or recommend a dose. Consult a qualified professional before changing a protocol.