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Small MoleculePreclinical

SR-9009 (Stenabolic)

es-ar-nine-zero-zero-nine

Research profile · How we handle evidence

Category

Small Molecule

Compound type

Phase / Status

Preclinical

Preclinical research only; human clinical trials and established dosing/safety are not available. Not an approved drug.

Standard Dose

20-30mg/day (split doses if oral, 10-20mg/day SubQ)

3x daily (oral) or 2x daily (SubQ)

Half-life

4-5 hours

Plasma elimination

Route(s)

OR

Oral

Research Stage

Preclinical

Animal/in-vitro data only; no human trial evidence.

Overview

SR-9009 targets Rev-ErbA proteins that help regulate the internal timing system and metabolism. In animal and cell studies, this has been linked to changes in mitochondrial biology and energy-related pathways. Human safety and effectiveness are not established.

Plain-language summary

SR-9009 targets Rev-ErbA proteins that help regulate the internal timing system and metabolism. In animal and cell studies, this has been linked to changes in mitochondrial biology and energy-related pathways. Human safety and effectiveness are not established.

Administration Routes

  • Oral

Also known as

StenabolicStenaSR9009Rev-Erb AgonistCardio in a BottleThe Clock Drug

Mechanisms

1

Rev-ErbA agonist — modulates circadian rhythm signaling and may increase mitochondrial biogenesis and metabolic activity.

Detailed mechanism

Rev-ErbA agonist - modulates circadian rhythm proteins to increase mitochondrial biogenesis and metabolic rate. Modulates cellular pathways and enzyme activity to produce therapeutic effects at the molecular level.

Safety

Side effects

  • Limited human safety data
  • Potential effects on sleep/circadian timing
  • Formulation and absorption can vary widely by route and product quality
  • Injection-related adverse events can occur if products are administered by injection

Reported benefits

  • Increased metabolic rate at rest
  • Improved endurance and stamina
  • Enhanced fat burning 24/7
  • Better sleep pattern regulation
  • Reduced inflammation
  • No hormonal suppression

Safety profile

Human safety and efficacy are not established. If considering any investigational compound, consult qualified medical professionals and avoid self-experimentation.

Clinical trials

Evidence is limited to preclinical studies in animal/cell models; no established clinical trial results in humans.

Structure

View 3D structure

Verified structure

SR-9009 (Stenabolic)

Exact 2D structure can be rendered from a PubChem-backed canonical SMILES string.

Verified via PubChemMatched by name stripped
Source: PubChemLookup: SR-9009InChIKey MMJJNHOIVCGAAP-UHFFFAOYSA-N
Chemical Formula
C20H24ClN3O4S
Molecular Weight
437.94 g/mol
CAS Number
1379686-30-2
InChIKey
MMJJNHOIVCGAAP-UHFFFAOYSA-N

Stack Context

Stacks with

CardarineOstarineLGD-4033

References

  1. 1

    Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists (Nature)

    2012

    View source
  2. 2

    Rev-erb-alpha modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy (Nature Medicine)

    2013

    View source
  3. 3

    Circadian integration of metabolism and energetics (Science)

    2010

    View source

This profile summarizes research literature for education only. It is not medical advice, and it does not diagnose, treat, or recommend a dose. Consult a qualified professional before changing a protocol.

Research-driven insights.Evidence-based decisions.