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HormoneApproved

Nandrolone (Deca-Durabolin)

NAN-droh-lone

Research profile · How we handle evidence

Category

Hormone

Compound type

Phase / Status

Approved

Historically used as an approved medication in some indications. It is a controlled substance in many regions and prohibited by most anti-doping organizations.

Standard Dose

200-600mg/week

Once weekly (long ester)

Half-life

Nandrolone Decanoate: ~6-12 days

Plasma elimination

Route(s)

IN / SU / OR

Intramuscular, Subcutaneous or Oral

Research Stage

Market Approved

Regulatory approval granted; post-market monitoring ongoing.

Overview

Deca is an anabolic steroid historically used for specific medical indications. In addition to potential benefits for muscle-related outcomes, it can alter prolactin and other hormone pathways, so side effects and monitoring are important.

Plain-language summary

Deca is an anabolic steroid historically used for specific medical indications. In addition to potential benefits for muscle-related outcomes, it can alter prolactin and other hormone pathways, so side effects and monitoring are important.

Administration Routes

  • Intramuscular
  • Subcutaneous
  • Oral

Also known as

DecaDeca-DurabolinNandro19-NortestosteroneNandrolone baseNPP baseNanDeca Dick compound

Mechanisms

1

19-nortestosterone derivative - binds androgen receptors with high affinity, also acts as progestogen. Raises prolactin via progestogenic activity. Basically turns your body into a muscle-building machine while messing with your hormones.

Detailed mechanism

19-nortestosterone derivative - binds androgen receptors with high affinity, also acts as progestogen. Raises prolactin via progestogenic activity. Binds to specific hormone receptors to regulate physiological processes including metabolism, tissue repair, and cellular function.

Safety

Side effects

  • Elevated prolactin and related sexual or mood effects
  • Changes in testosterone and fertility parameters
  • Fluid retention and blood pressure changes in some people
  • Hair loss/acne in susceptible individuals
  • Potential impact on liver enzymes is possible (monitoring may be needed)

Reported benefits

  • Significant lean muscle mass gains
  • Joint pain relief (collagen synthesis boost)
  • Lower androgenic side effects vs testosterone
  • Increases red blood cell production (FDA approved for anemia)
  • Well-studied with decades of medical use
  • Enhanced recovery

Safety profile

Well-characterized safety profile from extensive clinical use and trials.

Clinical trials

Completed clinical trials leading to FDA or regulatory approval.

Structure

View 3D structure

Verified structure

Nandrolone (Deca-Durabolin)

Exact 2D structure can be rendered from a PubChem-backed canonical SMILES string.

Verified via PubChemMatched by casNumber
Source: PubChemLookup: 360-70-3InChIKey JKWKMORAXJQQSR-UHFFFAOYSA-N
Chemical Formula
C28H44O3
Molecular Weight
428.66 g/mol (decanoate ester)
CAS Number
360-70-3
InChIKey
JKWKMORAXJQQSR-UHFFFAOYSA-N

Stack Context

Stacks with

TestosteroneCabergolineAnastrozoleBPC-157

References

  1. 1

    Effects of androgenic-anabolic steroids in athletes (Sports Medicine)

    2004

    View source
  2. 2

    Anabolic effects of nandrolone decanoate in patients receiving dialysis: a randomized controlled trial (JAMA)

    1999

    View source
  3. 3

    Pharmacology of anabolic steroids (British Journal of Sports Medicine)

    2008

    View source

This profile summarizes research literature for education only. It is not medical advice, and it does not diagnose, treat, or recommend a dose. Consult a qualified professional before changing a protocol.

Research-driven insights.Evidence-based decisions.