Masteron Enanthate
MAS-ter-on en-ANth-ate
Category
Compound type
Phase / Status
Controlled substance
Standard Dose
As directed
Half-life
Plasma elimination
Route(s)
Oral, Injectable or Topical
Research Stage
Research phase not specified; exercise appropriate caution.
Overview
If you see Masteron Enanthate discussed online, it is usually the longer-acting (enanthate) ester of drostanolone. Because it is DHT-derived, it is not designed to aromatize into estrogen the way some other steroids can. That said, "no estrogen conversion" does not mean "no risk": androgenic side effects (for example acne or hair shedding in people who are genetically prone) and changes to blood lipids have been reported with androgen exposure. Any use outside approved medical indications is educational only and should be treated as investigational, with a clinician involved for risk assessment.
Plain-language summary
If you see Masteron Enanthate discussed online, it is usually the longer-acting (enanthate) ester of drostanolone. Because it is DHT-derived, it is not designed to aromatize into estrogen the way some other steroids can. That said, "no estrogen conversion" does not mean "no risk": androgenic side effects (for example acne or hair shedding in people who are genetically prone) and changes to blood lipids have been reported with androgen exposure. Any use outside approved medical indications is educational only and should be treated as investigational, with a clinician involved for risk assessment.
Administration Routes
- Oral
- Injectable
- Topical
Also known as
Mechanisms
DHT-derived anabolic steroid
Detailed mechanism
Masteron Enanthate is drostanolone conjugated with the heptanoate (enanthate) ester at the C-17 hydroxyl, forming a depot that releases free drostanolone over 8-10 days as esterases in serum and tissue hydrolyze the ester bond. The liberated drostanolone, a 2-methyl DHT derivative, binds the androgen receptor to activate anabolic gene programs in skeletal muscle while being structurally incapable of aromatization due to the absence of an aromatizable C-19 angular methyl group. The longer release profile relative to the propionate ester allows twice-weekly injections to maintain stable plasma concentrations, but the extended depot also means that androgenic side effects and HPG axis suppression persist well past the final injection, with detectable drug remaining for several weeks.
Safety
Side effects
- Hair loss
- Acne
- Cholesterol issues
- Virilization in women
Reported benefits
- Muscle hardening
- No estrogen conversion
- Good for cutting
Safety profile
Consult medical professional before use
Clinical trials
See research status
Structure
Verified structure
Masteron Enanthate
Exact 2D structure can be rendered from a PubChem-backed canonical SMILES string.
- Chemical Formula
- C27H44O3
- Molecular Weight
- 416.6 g/mol
- CAS Number
- 13425-31-5
- InChIKey
- ZNYZYASFVYLKPE-SRGKWKMDSA-N
Stack Context
No stack data available.
References
- 1View source
Drostanolone Enanthate - PubChem Compound Record (NLM)
- 2View source
Drostanolone (PIM 901) - WHO International Programme on Chemical Safety, absorption and ester-related pharmacology (INCHEM)
1993
- 3View source
Drostanolone propionate pharmacokinetics and detection in urine (PubMed)
1990
- 4View source
Adverse Effects of Anabolic-Androgenic Steroids: A Literature Review (PMC)
2021
This profile summarizes research literature for education only. It is not medical advice, and it does not diagnose, treat, or recommend a dose. Consult a qualified professional before changing a protocol.