Andarine (S4)
AN-dar-in
Category
Compound type
Phase / Status
Research chemical, not approved for human use
Standard Dose
Half-life
Plasma elimination
Route(s)
Oral
Research Stage
Research phase not specified; exercise appropriate caution.
Overview
Andarine - often called S4 - is a SARM that binds to androgen receptors. People typically use it with the goal of building or maintaining lean tissue while cutting calories. A well-known downside is vision-related side effects reported by some users (often described as changes in night vision or color perception). Because long-term human safety data is limited, treat any performance claims as uncertain and avoid "stacking for shortcuts." If you're considering it, it's best to talk to a qualified clinician first.
Plain-language summary
Andarine - often called S4 - is a SARM that binds to androgen receptors. People typically use it with the goal of building or maintaining lean tissue while cutting calories. A well-known downside is vision-related side effects reported by some users (often described as changes in night vision or color perception). Because long-term human safety data is limited, treat any performance claims as uncertain and avoid "stacking for shortcuts." If you're considering it, it's best to talk to a qualified clinician first.
Administration Routes
- Oral
Also known as
Mechanisms
Selective androgen receptor modulator
Detailed mechanism
Selective modulator of androgen receptors with anabolic effects in muscle and bone while minimizing androgenic effects in other tissues.
Safety
Side effects
- Testosterone suppression
- Vision-related effects
- Mood changes
- Lipid changes
Reported benefits
- Increased muscle mass
- Fat loss support
- Strength gains
Safety profile
Limited human safety data. Vision side effects have been reported. Use only in research settings.
Clinical trials
Phase II trials for muscle wasting conditions. Not approved for human consumption.
Structure
Verified structure
Andarine (S4)
Exact 2D structure can be rendered from a PubChem-backed canonical SMILES string.
- Chemical Formula
- C19H18F3N3O6
- Molecular Weight
- 441.4 g/mol
- CAS Number
- 401900-40-1
- InChIKey
- YVXVTLGIDOACBJ-SFHVURJKSA-N
Stack Context
Stacks with
References
- 1View source
Pharmacokinetics and pharmacodynamics of nonsteroidal androgen receptor ligands
2006
- 2View source
Selective Androgen Receptor Modulator (SARM) treatment prevents bone loss and reduces body fat in ovariectomized rats
2007
- 3View source
Nonsteroidal selective androgen receptor modulators (SARMs): dissociating the anabolic and androgenic activities of the androgen receptor for therapeutic benefit
2009
- 4View source
Detection of selective androgen receptor modulators in sports drug testing: a review of analytical approaches
2010
This profile summarizes research literature for education only. It is not medical advice, and it does not diagnose, treat, or recommend a dose. Consult a qualified professional before changing a protocol.